Announcement PDF Form 605 Corporations Law Section 671B Notice of ceasing to be a substantial holder To: Company Name/Scheme STARPHARMA HOLDINGS LIMITED ACN/ARSN 078 532 180 1. Details of substantial holder (1) Name UBS Group AG and its related bodies corporate ACN/ARSN (if applicable): The holder ceased to be a substantial shareholder on 11 September 2026 The previous notice was given to the company on 11 September 2026 The previous notice was dated 09 September 2026 2. Changes in relevant interests Particulars of each change in, or change in the nature of, a relevant interest (2) of the substantial holder or an associate (3) in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows: Date of change Person whose relevant interest changed Nature of Change (4) Consideration given in relation to change (5) Class (6) and Number of securities affected Person’s votes affected Please see Appendix A. 3. Changes in association The persons who have become associates (3) of, ceased to be associates of, or have changed the nature of their association (7) with, the substantial holder in relation to voting interests in the company or scheme are as follows: Name and ACN/ARSN (if applicable) Nature of association N/A N/A 4. Addresses The addresses of persons named in this form are as follows: Name Address N/A N/A SIGNATURE Print Name: Ruby Ko Capacity: Authorised signatory Sign Here: Date: 15-September--2026 Contact details for this notice: --------------------------------------------------------------- Ruby Ko Group Compliance, Operational Risk Control. (T) +852 3712 2802 --------------------------------------------------------------- SPL - Appendix A Date of change Person whose relevant interest changed Nature of Change Consideration given in relation to change Number of securities Class 10-Sep-26 UBS Securities Australia Ltd Sell 57,062 (72,691) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 962 1,188 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 12,785 16,287 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 10,974 (13,980) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 26,275 33,471 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 60,752 75,637 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 9,298 11,550 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 31,082 (39,595) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 65,048 80,966 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 178,364 (223,963) Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 10,955 (13,631) Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 21,661 (27,164) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 17,692 22,392 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 310 387 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 9,358 11,728 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 9,077 11,272 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 14,503 (18,122) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 92,601 116,994 Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 12,617 15,368 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 199,747 (249,279) Ordinary 10-Sep-26 UBS Securities Australia Ltd Buy 26,265 32,901 Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 939 (1,196) Ordinary 10-Sep-26 UBS Securities Australia Ltd Sell 12,311 (15,462) Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 134,085 (183,981) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 19,143 25,999 Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 567,815 805,411 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 394,522 (529,205) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 38,159 51,241 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 14,027 (18,700) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 16,958 23,066 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 16,438 (22,936) Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 92 (130) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 20,874 29,608 Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 25,431 34,666 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 9,008 (12,778) Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 281,679 (378,448) Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 15,439 (19,793) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 79,316 104,749 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 122,330 (166,006) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 28,783 38,434 Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 752 1,006 Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 16,999 23,499 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 195,606 (262,735) Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 344,115 461,218 Ordinary 11-Sep-26 UBS Securities Australia Ltd Buy 21,753 29,210 Ordinary 11-Sep-26 UBS Securities Australia Ltd Sell 615,574 (833,547) Ordinary 11-Sep-26 UBS AG London Branch Return of Rehypothecated position N/A (283,398) Ordinary