Announcement PDF Form 604 Corporations Act 2001 Section 671B Notice of Change of Interests of Substantial Holder To: Starpharma Holdings Ltd ACN/ARSN: 1. Details of substantial holder (s) Name: FIL Limited and the entities listed in Annexure A (“FIL”) ACN/ARSN (if applicable) There was a change in the interests of the substantial holder on The previous notice was given to the company on The previous notice was dated 26 June 2015 9 June 2015 9 June 2015 2. Previous and present voting power The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows: Class of Securities (4) Common Stock Present Notice Present Notice Previous Previous Notice Voting Power (5) Person’s votes Voting Power (5) Notice Person’s votes 16,106,957 5.05% 19,654,406 6.16% 3. Changes in relevant interests Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows: Date of Change 2015/06/09 2015/06/10 2015/06/11 2015/06/12 2015/06/12 2015/06/15 2015/06/15 2015/06/16 2015/06/16 Person whose relevant interest changed FIL FIL FIL FIL FIL FIL FIL FIL FIL Nature of change (6) BUY BUY BUY BUY BUY BUY BUY BUY BUY Consideration given in relation to change (7) AUD$ 0.73 0.75 0.76 0.77 0.77 0.75 0.75 0.75 0.75 Class and number of securities affected Person’s votes affected Common Stock 288,406 10,741 7,628 52,327 59,683 495,489 16,974 207,909 8,585 Common Stock 288,406 10,741 7,628 52,327 59,683 495,489 16,974 207,909 8,585 2015/06/17 2015/06/17 2015/06/19 2015/06/19 2015/06/19 2015/06/25 2015/06/25 2015/06/26 2015/06/26 FIL FIL FIL FIL FIL FIL FIL FIL FIL BUY BUY BUY BUY BUY BUY BUY BUY 0.78 0.78 0.78 0.78 0.78 0.72 0.74 0.73 91,721 8,279 114,259 257,132 6,123 300,000 402,091 119,446 91,721 8,279 114,259 257,132 6,123 300,000 402,091 119,446 BUY 0.72 Total Buy 1,100,656 3,547,449 1,100,656 3,547,449 4. Present Relevant Interest Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows: Refer to Annexure A 5. Changes in Association The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows: NA 6. Addresses The addresses of persons named in this form are as follows: Refer to Annexure A Sign Here: _______________________________ Dated: 30 June 2015 Kelvin Lo Head of Regulatory Reporting, Asia Pacific Duly authorized under Powers of Attorney on behalf of FIL Limited Annexure A Investment Manager Address Custodian FIL INVESTMENT MANAGEMENT (AUSTRALIA) LIMITED Level 11, 167 Macquarie Street, Sydney, NSW 2000 FIL INVESTMENT MANAGEMENT (HONG KONG) LIMITED Suite 2201, Level 22, Two Pacific Place, 88 Queensway, Admiralty, Hong Kong FIL PENSION MANAGEMENT Grand Total Pembroke Hall, 42 Crow Lane, Pembroke, Bermuda JP MORGAN, BOURNEMOUTH (C) NATIONAL ASTL BK MELBOURNE (S) Investment Discretion/ Voting Power NORTHERN TRUST LONDON (C) BROWN BROS HARRIMN LTD LUX (C) CLEARSTREAM BANKING SA LUX (C) Investment Discretion/ Voting Power MASTER TRUST BANK OF JAPAN (C) NATIONAL ASTL BK MELBOURNE (S) Investment Discretion/ Voting Power Nature of Relevent Interest Sum of Numerator Shares 76,844 200,058 143,398 17,067,805 358,184 707,461 1,100,656 19,654,406