Announcement PDF Form 605 Corporations Law Section 671B Notice of ceasing to be a substantial holder To: Company Name/Scheme STARPHARMA HOLDINGS LIMITED ACN/ARSN 078 532 180 1. Details of substantial holder (1) Name UBS Group AG and its related bodies corporate ACN/ARSN (if applicable): The holder ceased to be a substantial shareholder on 23 September 2026 The previous notice was given to the company on 22 September 2026 The previous notice was dated 18 September 2026 2. Changes in relevant interests Particulars of each change in, or change in the nature of, a relevant interest (2) of the substantial holder or an associate (3) in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows: Date of change Person whose relevant interest changed Nature of Change (4) Consideration given in relation to change (5) Class (6) and Number of securities affected Person’s votes affected Please see Appendix A. 3. Changes in association The persons who have become associates (3) of, ceased to be associates of, or have changed the nature of their association (7) with, the substantial holder in relation to voting interests in the company or scheme are as follows: Name and ACN/ARSN (if applicable) Nature of association N/A N/A 4. Addresses The addresses of persons named in this form are as follows: Name Address N/A N/A SIGNATURE Print Name: Ruby Ko Capacity: Authorised signatory Sign Here: Date: 25-September-2026 Contact details for this notice: --------------------------------------------------------------- Ruby Ko Group Compliance, Operational Risk Control. (T) +852 3712 2802 --------------------------------------------------------------- SPL - Appendix A Date of change Person whose relevant interest changed Nature of Change Consideration given in relation to change Number of securities Class 21-Sep-26 UBS Securities Australia Ltd Sell 181 (226) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 19,224 (24,227) Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 19,125 24,227 Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 4,932 (6,204) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 32,532 (41,039) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 108 (135) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 4,584 (5,730) Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 238,024 299,627 Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 46,958 59,208 Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 51,462 (64,814) Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 7,498 9,431 Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 11,001 13,943 Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 1 (1) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 3,118 (3,917) Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 86,869 (109,352) Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 70,574 88,728 Ordinary 21-Sep-26 UBS Securities Australia Ltd Sell 225,152 (284,355) Ordinary 21-Sep-26 UBS Securities Australia Ltd Buy 236,168 294,400 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 2,681 (3,331) Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 11,434 (14,206) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 51,285 63,700 Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 2 2 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 800 (991) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 4,818 6,009 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 24,024 (29,807) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 2,711 3,347 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 26,029 (32,246) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 153,768 191,635 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 62,795 (78,278) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 89,095 110,870 Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 33,628 41,789 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 4,856 (6,005) Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 137,533 (170,531) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 282,854 353,479 Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 10,367 13,038 Ordinary 22-Sep-26 UBS Securities Australia Ltd Sell 82,682 (102,953) Ordinary 22-Sep-26 UBS Securities Australia Ltd Buy 206,611 255,929 Ordinary 22-Sep-26 UBS AG London Branch Return of Rehypothecated position N/A (500,000) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 29,420 35,648 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 14,518 (17,716) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 20,196 24,480 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 28,837 (35,026) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 35,824 43,083 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 9,111 (11,158) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 14,154 17,367 Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 54,852 66,142 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 24,560 (30,310) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 45,252 55,531 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 44,146 (54,267) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 8,523 10,301 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 8,441 (10,464) Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 258,793 (314,260) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 329,151 401,599 Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 44,306 54,190 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 77,122 (93,075) Ordinary 23-Sep-26 UBS Securities Australia Ltd Buy 441,960 533,897 Ordinary 23-Sep-26 UBS Securities Australia Ltd Sell 174,307 (214,426) Ordinary 23-Sep-26 UBS AG London Branch Return of Rehypothecated position N/A (2,350,000) Ordinary 23-Sep-26 UBS AG London Branch Return of Rehypothecated position N/A (16,971,369) Ordinary