Increasing Solubility

By joining the drug to a dendrimer construct, very large increases in drug solubility have been achieved, which can enhance the “bioavailability” of the drug. 

For example Docetaxel is a cancer drug well known for its poor aqueous solubility. When conjugated to a dendrimer construct a 20,000 fold increase in solublised Docetaxel is achieved.

The formulation of DEP® docetaxel is also Polysorbate 80-free.


DEP® docetaxel (vial on right) 20,000 x increase in water solubility


Download DEP® Drug Delivery Summary ( pdf file, 1007kb) or Contact Us for further information.