Investor Webinar - Starpharma and Medicxi Partnership: Petalion Therapeutics (9 April 2024)

Apr 10th, 2024

Starpharma hosted an investor webinar on Tuesday, 9 April 2024. The session focused on the ASX Announcement lodged on 8 April 2024, 'Starpharma and Medicxi Partnership Petalion Therapeutics', about the strategic partnership with Medicxi and the formation of a new company called Petalion Therapeutics.

Investor Webinar Notification – Starpharma x Medicxi Partnership (ASX Announcement)

Apr 8th, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) is pleased to announce that it will host an investor webinar on Tuesday, 9 April 2024.

Medicxi and Starpharma create Petalion Therapeutics to develop novel dendrimer-based treatments (ASX Announcement)

Apr 8th, 2024

Medicxi to invest up to USD $25M into newly established entity, Petalion Therapeutics, led by highly experienced pharmaceutical executive Dr Mehdi Shahidi

Half Yearly Report and Accounts (ASX Announcement)

Feb 28th, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today releases its Interim Report and Half-Year Financial Results for the period ended 31 December 2023 (H1 FY24).

VivaGel® BV US FDA Appeal Outcome (ASX Announcement)

Feb 19th, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces that it has completed the formal dispute resolution process with the US Food and Drug Administration (FDA) in relation to VivaGel^® BV. The FDA has maintained its position that they require additional clinical efficacy data to be generated for the regulatory approval of VivaGel^® BV for bacterial vaginosis (BV) in the US. The formal dispute resolution process involved multiple submissions, meetings, detailed analyses, and the preparation of regulatory precedents relating to recent product approvals. Starpharma was supported through this process by highly experienced regulatory advisers, key opinion leaders, and biostatistical and legal advisers, including several who were ex-FDA.

Quarterly Activities Report & Appendix 4C (ASX Announcement)

Jan 31st, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today releases its Quarterly Activities Report and Appendix 4C for the period ended 31 December 2023 (Q2 FY24). Starpharma’s closing cash balance as at 31 December 2023 was $32.1 million.

Viraleze shows antiviral efficacy in COVID-19 patients (ASX Announcement)

Jan 29th, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces the results of the post-market clinical study of Viraleze™ nasal spray in participants with COVID-19, demonstrating that Viraleze™ reduced SARS-CoV-2 viral load in the nose, increased the rate of virus clearance from the nose, improved key symptoms of COVID-19, including loss of smell (anosmia), and was well-tolerated.

VivaGel® BV sales and distribution agreement – MENA region (ASX Announcement)

Jan 22nd, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces it has signed a sales and distribution agreement for its VivaGel^® BV product with ITROM Pharmaceutical Group, covering 13 countries across the Middle East and North Africa (MENA) region. In this region, the prevalence of bacterial vaginosis among a female population of 238 million is 25%, indicating a high need for new effective therapeutic approaches and a significant opportunity for VivaGel^® BV.

DEP® cabazitaxel data presentation at ASCO GI cancer meeting (ASX Announcement)

Jan 19th, 2024

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces the presentation of the positive results from its Phase 2 clinical trial of DEP^® cabazitaxel at the American Society of Clinical Oncology (ASCO) Gastrointestinal (GI) Cancers Symposium, which is being held from 18 to 20 January 2024 in San Francisco, US. ASCO is the world's leading professional organisation for physicians and oncology professionals. The ASCO GI Cancers Symposium is the only global meeting of its kind focusing on the latest innovative science and clinical developments in GI cancer treatment, research, and care. It brings together oncology thought leaders, practising clinicians, novel drug developers, and GI specialists from around the world.

Starpharma to present DEP® at Radiopharmaceuticals Summit (ASX Announcement)

Dec 6th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces it is presenting at the Targeted Radiopharmaceuticals Summit Europe, having been invited to present at the specialist radiotheranostics conference being held in Berlin, Germany, from 5 to 7 December 2023.

Notice of Annual General Meeting 2023 - Clarification (ASX Announcement)

Nov 15th, 2023

Starpharma refers to its Notice of Annual General Meeting dated 27 October 2023 (Notice).

Starpharma announces new CEO, Ms Cheryl Maley (ASX Announcement)

Nov 10th, 2023

Starpharma is today pleased to announce the appointment of Ms Cheryl Maley as Chief Executive Officer (CEO) and Managing Director of Starpharma effective 8 January 2024.

Quarterly Activities Report & Appendix 4C (ASX Announcement)

Oct 31st, 2023

Starpharma today releases its Quarterly Activities Report and Appendix 4C for the period ended 30 September 2023 (Q1 FY24).

Positive DEP® Cabazitaxel Phase 2 Results in Multiple Cancers (ASX Announcement)

Oct 18th, 2023

Starpharma today announces the final positive results from its completed Phase 2 open-label clinical trial of DEP^® cabazitaxel. The trial met its objectives, with endpoints demonstrating positive anti-tumour efficacy of DEP^® cabazitaxel in advanced, metastatic castrate-resistant prostate cancer (mCRPC), as well as other difficult-to-treat cancers, including platinum-resistant ovarian cancer and gastro-oesophageal cancers.

DEP® irinotecan IO/PARP combination data presented at AACR (ASX Announcement)

Oct 16th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today provides a copy of the DEP® irinotecan combination data poster, showcasing the recently announced1 data for DEP® irinotecan in combination with leading anticancer therapies, including immuno-oncology (IO) agents, in human colorectal cancer (CRC) models.

DEP® irinotecan clinical data presented at AACR meeting (ASX Announcement)

Oct 16th, 2023

Starpharma today provides a copy of the DEP® irinotecan clinical poster, highlighting the recently announced1 positive interim clinical data from Starpharma’s Phase 1/2 clinical trial, which demonstrated durable anti-tumour responses in advanced colorectal cancer (CRC) and platinum-resistant/refractory ovarian cancer.

DEP® theranostic presented at international oncology meeting (ASX Announcement)

Oct 16th, 2023

Starpharma today provides a copy of the poster that showcases the results from a study of DEP® HER2-zirconium, Starpharma’s HER2-targeted radiodiagnostic candidate, which demonstrated a favourable biodistribution profile, with excellent imaging contrast between tumour and normal tissues, as well as rapid uptake and high levels of tumour accumulation in a HER2+ breast cancer model.

Date of Starpharma’s Annual General Meeting 2023 (ASX Announcement)

Oct 2nd, 2023

Starpharma today announces, in accordance with ASX Listing Rule 3.13.1, that its 2023 Annual General Meeting (AGM) will be held at 2:00 p.m. (Melbourne time) on Wednesday, 29 November 2023.

DEP® irinotecan combination data to be presented at international oncology conference (ASX Announcement)

Sep 27th, 2023

Starpharma today announces the presentation of data that demonstrate the benefits of combining DEP^® irinotecan with other important classes of anti-cancer therapies, including immuno-oncology (IO) agents, in models of human colorectal cancer.

Starpharma featured on ShareCafe

Sep 22nd, 2023

Starpharma interviewed for Fear and Greed podcast

Sep 22nd, 2023

Starpharma interviewed for ausbiz

Sep 15th, 2023

Positive DEP® irinotecan clinical results to be presented at international oncology conference (ASX Announcement)

Sep 13th, 2023

Starpharma today announces positive interim results from its Phase 1/2 clinical trial of DEP^® irinotecan will be presented at the upcoming American Association of Cancer Research (AACR), National Cancer Institute (NCI) and European Organisation for Research and Treatment of Cancer (EORTC) International Conference on Molecular Targets and Cancer Therapeutics in Boston, US, from 11 to 15 October 2023.

Change of Company Secretary (ASX Announcement)

Aug 28th, 2023

Starpharma today announces, in accordance with ASX Listing Rule 3.16.1, that Tracy Weimar has resigned as Company Secretary, a role that was conducted for an interim period.

Appendix 4G – Corporate Governance Statement (ASX Announcement)

Aug 24th, 2023

Starpharma today releases its Appendix 4G – Key to Disclosures Corporate Governance Council Principles and Recommendations, in accordance with ASX Listing Rules 4.7.3 and 4.10.3.

Starpharma annual report and full-year financial results (ASX Announcement)

Aug 24th, 2023

Starpharma today releases its annual report and full-year financial results for the year ended 30 June 2023.

Quarterly Activities Report & Appendix 4C (ASX Announcement)

Jul 31st, 2023

Starpharma today releases its Quarterly Activities Report and Appendix 4C for the period ended 30 June 2023 (Q4 FY23).

Partnered program update (ASX Announcement)

Jul 31st, 2023

Following communication from AstraZeneca on Friday, 28 July 2023, and the subsequent release of AstraZeneca’s H1 and Q2 2023 results announcement that day, Starpharma (ASX: SPL, OTCQX: SPHRY) reports that AstraZeneca has made the decision to discontinue the development of AZD0466, after an internal review, prompted by a small number of asymptomatic adverse events (AEs) that were unrelated to Starpharma’s dendrimer drug delivery technology.

DEP® HER2-radiodiagnostic shows imaging benefits (ASX Announcement)

Jul 21st, 2023

Starpharma today announces that DEP^® HER2-zirconium, its HER2-targeted radiodiagnostic candidate, has demonstrated a favourable biodistribution profile, with excellent imaging contrast between tumour and normal tissues, as well as rapid uptake and high levels of tumour accumulation in a HER+ breast cancer model.

Clinical trial update (ASX Announcement)

Jun 27th, 2023

A voluntary partial clinical hold has been implemented on a trial in which Starpharma (ASX: SPL, OTCQX: SPHRY) technology is used: AZD0466 Monotherapy or in Combination in Patients with Advanced Haematological Malignancies (NCT04865419).

Life Sciences Investor Presentation (ASX Announcement)

Jun 23rd, 2023

Further to yesterday’s announcement, Starpharma (ASX: SPL, OTCQX: SPHRY) provides a copy of the investor presentation that was aired during the OTCQX’s Virtual Life Sciences Investor Forum on Thursday, 22 June 2023 at 10:00 am EDT (Friday, 23 June 2023, at 12:00 am AEST).

Starpharma to present at Life Sciences Investor Forum (ASX Announcement)

Jun 22nd, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces that an investor presentation by Chief Executive Officer, Dr Jackie Fairley, will be broadcast at 10:00 am EDT on Thursday, 22 June 2023 (12:00 am AEST on Friday, 23 June 2023), as part of the OTCQX’s Virtual Life Sciences Investor Forum.

AZD0466 clinical data presented by AstraZeneca at EHA Congress (ASX Announcement)

Jun 14th, 2023

Starpharma today announces the presentation of AZD0466 clinical data by AstraZeneca at the European Hematology Association 2023 Hybrid Congress (EHA Congress), which was held from 8 - 11 June 2023.

Starpharma CEO to retire in 2024 (ASX Announcement)

Jun 9th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) wishes to advise that following her significant tenure as the Company’s Chief Executive Officer (CEO), Dr Jackie Fairley has advised the Board that she intends to retire during 2024. Jackie and the Board are keen to ensure an orderly transition and have agreed that she will continue in the role until a successor is ready to commence, providing leadership and continuity throughout the transition period.

VIRALEZE™ Nasal Spray Approved in Malaysia (ASX Announcement)

Jun 5th, 2023

Starpharma today announces that it has achieved regulatory approval for its antiviral nasal spray product, VIRALEZE™, in Malaysia. The registration will allow Starpharma and its commercial partners to market and sell the product in Malaysia, a country with a population of over 33 million.

Quarterly Activities Report & Appendix 4C (ASX Announcement)

Apr 28th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today releases its Quarterly Activities Report and Appendix 4C for the period ended 31 March 2023 (Q3 FY23). Starpharma’s net operating cash outflows for the quarter were $4.9 million, and the closing cash balance as at 31 March 2023 was $38.9 million.

HER2-targeted DEP® SN-38 ADC outperforms in HER2+ human cancer model (ASX Announcement)

Apr 26th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces that it has developed a HER2-targeted DEP^® SN-38 antibody-drug conjugate (ADC), which has shown significant anti-tumour activity in a HER2+ human ovarian cancer xenograft model, outperforming the approved ADC product, Enhertu^®[1].

AZD0466 active in small cell lung cancer patient models (ASX Announcement)

Apr 20th, 2023

Starpharma (ASX: SPL, OTCQX: SPHRY) today announces AZD0466 results from a preclinical study in small cell lung cancer (SCLC) patient-derived xenograft (PDX) models. Starpharma’s partner, AstraZeneca, presented these results overnight at the American Association for Cancer Research (AACR) Annual Meeting.

DEP® cabazitaxel Phase 2 clinical trial completes enrolment and treatment (ASX Announcement)

Apr 17th, 2023

Starpharma today announces that it has completed enrolment and treatment of patients for the Phase 2 clinical trial of its investigational anticancer product DEP^® cabazitaxel. Encouraging efficacy signals, including significant tumour shrinkage and substantial tumour biomarker reductions, have been observed in multiple cancer types, including prostate cancer, ovarian cancer, gastro-oesophageal cancer, cholangiocarcinoma and head and neck cancer, following treatment with DEP^® cabazitaxel.

Commencement of CFO and Company Secretary (ASX Announcement)

Apr 3rd, 2023

Melbourne, Australia; 3 April 2023: Starpharma (ASX: SPL, OTCQX: SPHRY) is pleased to announce that, further to the announcement on 3 March 2023, Mr Justin Cahill commences in the role of Chief Financial Officer (CFO) and Company Secretary today. 

Starpharma presents at ASX Small and Mid-Cap Conference (ASX Announcement)

Mar 22nd, 2023

Melbourne, Australia; 22 March 2023: Starpharma (ASX: SPL, OTCQX: SPHRY) announces that Starpharma CEO Dr Jackie Fairley will present a brief overview of the Company at the ASX Small and Mid-Cap Conference today at 11:00am AEDT. The Conference showcases selected ASX-listed companies to Australian investors.

CFO and Company Secretary Appointment (ASX Announcement)

Mar 3rd, 2023

Melbourne, Australia; 3 March 2023: Starpharma Holdings Limited (ASX: SPL, OTCQX: SPHRY) is pleased to announce the appointment of Mr Justin Cahill as Chief Financial Officer (CFO) and Company Secretary, following an extensive executive search process. Justin will commence in the role in early April 2023.

Interim Report and Half-Year Financial Results - H1FY23 (ASX Announcement)

Feb 28th, 2023

Melbourne, Australia; 28 February 2023: Starpharma Holdings Limited (ASX: SPL, OTCQX: SPHRY) today releases its interim report and half-year financial results for the period ended 31 December 2022 (H1 FY23).

Appointment of Company Secretary (ASX Announcement)

Feb 1st, 2023

Starpharma Holdings Limited (ASX: SPL, OTCQX: SPHRY) advises, in accordance with ASX Listing Rule 3.16.1, that Ms Tracy Weimar from Vistra Australia has been appointed as interim Company Secretary, effective today.

Dr Russell Basser appointed as non-executive director (ASX Announcement)

Jan 31st, 2023

The Board of Starpharma Holdings Limited (ASX: SPL, OTCQX: SPHRY) is pleased to announce the appointment of Dr Russell Basser as an independent non-executive director, effective from 20 February 2023.

Dr Basser is a medical oncologist and former corporate executive with over 30 years of international medical and biopharmaceutical experience, including 21 years at CSL.

Dr Basser has substantial expertise in international drug and vaccine development, having held multiple senior executive roles whilst at CSL, including Senior Vice President (SVP) of Research and Development at CSL Seqirus; Chief Medical Officer at CSL Limited / CSL Behring; and SVP of Global Clinical Research and Development at CSL Behring / CSL Limited.

Quarterly Activities Report & Appendix 4C (ASX Announcement)

Jan 30th, 2023

Starpharma Holdings Limited (ASX: SPL, OTCQX: SPHRY) today releases its Quarterly Activities Report and Appendix 4C for the period ended 31 December 2022 (Q2 FY23).

Starpharma’s cash balance as at 31 December 2022 was $44.0 million, with a positive net operating cash flow of $2.2 million for the quarter. Total receipts of $8.1 million in the quarter include $7.1 million received from the Australian Government under its R&D tax incentive scheme and receipts from customers of $1.0 million. Customer receipts, including from sales of VIRALEZE™ and VivaGel^® BV, were up 59% from the previous quarter (Q1 FY23: $0.6 million).

Resignation of CFO / Company Secretary

Dec 21st, 2022

Starpharma today announces that after nearly 17 years with the Company, including 14 years as Chief Financial Officer (CFO), Mr Nigel Baade, has advised of his intention to leave Starpharma in early 2023 to pursue new professional opportunities. 

Positive AZD0466 clinical data presented by AstraZeneca (ASX Announcement)

Dec 13th, 2022

Starpharma today announces preliminary AZD0466 clinical trial results from the ongoing Phase 1/2 trial in patients with advanced relapsed/refractory leukemia (NCT04865419), presented by Starpharma’s partner AstraZeneca at the 2022 American Society of Hematology (ASH) Annual Meeting today.

Starpharma presents additional clinical data for DEP® cabazitaxel in prostate cancer (ASX Announcement)

Sep 12th, 2022

Starpharma announces additional results from the mCRPC cohort of its Phase 2 DEP^® cabazitaxel trial, following completion of dosing in this cohort. Treatment with DEP^® cabazitaxel showed a number of key advantages compared to published data for conventional cabazitaxel, including superior efficacy, as measured by longer PFS, and a lower incidence of key side effects, despite this patient cohort being relatively more heavily pre-treated.

Starpharma signs new DEP® agreement with MSD (ASX Announcement)

Aug 10th, 2022

Starpharma today announced it has signed a new DEP^® Research Agreement with MSD, the trade name of Merck Sharp & Dohme LLC, Rahway, NJ, USA. This new agreement follows an earlier DEP^® Antibody Drug Conjugate (ADC) agreement signed with MSD in February 2021. Under the new agreement, Starpharma will design and synthesize a number of DEP^® dendrimer conjugates and will provide them to MSD for testing and characterisation.